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Amlitelimab

CAT: 0804-HY-P99434-01Size: 1 mgDry Ice: YesHazardous: No
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CAT#:0804-HY-P99434-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Amlitelimab () is an anti-OX40 Ligand (OX40L) monoclonal antibody (mAb) . Amlitelimab inhibits OX40-OX40L interaction, and can be used in the research of atopic dermatitis[1][2][3].
CAS Number
2378692-15-8
Product Name Alternative
KY1005; SAR445229
UNSPSC
12352203
Target
Others
Type
Inhibitory Antibodies
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/amlitelimab.html
Purity
98.23
Solubility
10 mM in DMSO
Smiles
[Amlitelimab]
Molecular Weight
(145.94 kDa)
References & Citations
[1]Ana Maria Lé, et al. OX40-OX40L Inhibition for the Treatment of Atopic Dermatitis-Focus on Rocatinlimab and Amlitelimab. Pharmaceutics 2022, 14 (12), 2753. |[2]Saghari M, et al. OX40L Inhibition Suppresses KLH-driven Immune Responses in Healthy Volunteers: A Randomized Controlled Trial Demonstrating Proof-of-Pharmacology for KY1005. Clin Pharmacol Ther. 2022 May;111 (5) :1121-1132. |[3]Tkachev V, et al. Combined OX40L and mTOR blockade controls effector T cell activation while preserving Treg reconstitution after transplant. Sci Transl Med. 2017 Sep 20;9 (408) :eaan3085.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 3

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