Anti-PPM1D Alexa Fluor® 647
CAT:
270-A6-894-C100
Size:
0.1 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Anti-PPM1D Alexa Fluor® 647
- Background: PPM1D is a Mg2+/Mn2+ dependent protein phosphatase 1D with inducible expression in response to various types of environmental stress. This expression is p53-dependent, and subsequently PPM1D negatively regulates the p53-mediated transcription, thus it suppresses the apoptosis. PPM1D contributes to development of carcinomas, and seems to be a promissing therapeutic target. Amplification of PPM1D is associated with breast cancer.
- Specifications: The mouse monoclonal antibody 7E11/C5 recognizes an epitope within the sequence FTNEDELYNLLTDSP of PPM1D, a protein phosphatase, which contributes to development of some carcinomas.
- CAS Number: 9007-83-4
- Certification: RUO
- Host: Mouse
- Species Reactivity: Mouse, Human
- Immunogen: Purified human PPM1D
- Target Antigen: PPM1D
- Isotype: IgG1
- Clone: 7E11/C5
- Applications: Flow cytometry: Recommended dilution: 1-5 μg/mL. Intracellular staining.
- Validated Applications: FC-IC, IHC-P, ICC
- Concentration: 0.1 mg/mL
- Format: Alexa Fluor® 647
- Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Storage Conditions: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.