Propiconazole

• Description:

  Propiconazole is an orally active N-substituted triazole used as a fungicide. Propiconazole is a mouse liver hepatotoxicant and a hepatocarcinogen that has adverse reproductive and developmental toxicities in experimental animals[1][2].

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H317, H360, H400, H410

• Target:

  Fungal; Reactive Oxygen Species (ROS)

• Type:

  Reference compound

• Related Pathways:

  Anti-infection; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/propiconazole.html

• Purity:

  99.92

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  CCCC1OC(CN2N=CN=C2)(C3=CC=C(Cl)C=C3Cl)OC1

• Molecular Formula:

  C15H17Cl2N3O2

• Molecular Weight:

  342.22

• Precautions:

  H302, H317, H360, H400, H410

• References & Citations:

  [1]Guobin Sun, et al. Propiconazole-induced cytochrome P450 gene expression and enzymatic activities in rat and mouse liver. Toxicol Lett. 2005 Feb 15;155 (2) :277-87.|[2]ShuangLi, et al. Single and Combined Cytotoxicity Research of Propiconazole and Nano-zinc Oxide on the NIH/3T3 Cell. Procedia Environmental Sciences Volume 18, 2013, Pages 100-105.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [60207-90-1]