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GW788388

CAT: 0421-82603-2Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0421-82603-2Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
GW788388 is a potent inhibitor of the TGF-β receptor type 1 (TβRI) and blocks the activation by TGF-β1 of Smad, having an impact on EMT (epithelial to mesenchymal transition of tissues and cells. The use of this inhibitor has proved relevant in the treatment of Chagas heart disease, by reducing cardiac fibrosis.
Description
GW788388 is an inhibitor of TGF-β receptor kinases ALK4 (, ALK5, ALK7, and TGFβRII.
CAS Number
452342-67-5
Purity
≥ 98% by HPLC
Solubility
Soluble in DMSO (18 mg/mL with warming)
Molecular Formula
C25H23N5O2
Shipping Conditions
-20°C
Storage Conditions
Upon receipt, store at -20°C. Stable for 2 years from date of receipt, when stored as directed. Solutions are stable for up to 1 month at -20°C.
Calculated Molecular Weight
425.49 Da

Alternative Products

CatalogName
A8301-5.1GW788388

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