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HAT1 (KAT1), FLAG-Tag Recombinant

CAT: 0421-102176-2Size: 100 µgDry Ice: YesHazardous: No
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CAT#:0421-102176-2Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
HAT1 (histone acetyltransferase 1), also known as KAT1, regulates chromatin structure, mitochondrial function, and DNA repair. HAT1 acetylates newly synthesized histones in the cytoplasm and succinylates histones and non-histone proteins. The epigenetic regulation activity of this protein is involved in a wide variety of diseases such as cancer, inflammatory diseases, and viral infections. The development of inhibitors targeting HAT1 may open new therapeutic avenues in those disorders.
Description
Recombinant human full-length HAT1 (histone acetyltransferase 1), also known as KAT1, amino acids 2-419 (end) . This construct contains an N-terminal FLAG-tag. The recombinant protein was affinity purified.
UniProt
O14929
Tag
N-terminal FLAG-tag
Applications
Useful for SDS-PAGE.
Purity
≥ 90%
Format
Aqueous buffer solution
Shipping Conditions
-80°C
Storage Conditions
At least 6 months at -80°C.
Calculated Molecular Weight
51 kDa
Formulation
40 mM Tris-HCl, pH 8.0,110 mM NaCl, 2.2 mM KCl, 80 ng/µl FLAG peptide, and 20% glycerol.

UniProtKB · O14929

Histone acetyltransferase type B catalytic subunit

HAT1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O14929
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
HAT1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.3.1.48
Processing
—
Secondary accessions
Q49A44, Q53QF0, Q53SU4, Q6P594, Q8WWB9
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Molecular function

AcyltransferaseTransferase

Coding sequence diversity

Alternative splicing

Cellular component

CytoplasmMitochondrionNucleus