I-BRD9

• Description:

  I-BRD9 is a selective cellular chemical probe for bromodomain-containing protein 9 (BRD9) . I-BRD9 has a pIC50value of 7.3 for BRD9 inhibitor, with greater than 700-fold selectivity over the BET family and 200-fold over the highly homologous bromodomain-containing protein 7 (BRD7) . I-BRD9 is also shows a greater than 70-fold selectivity against a panel of 34 bromodomains. I-BRD9 downregulates CLEC1, DUSP6, FES and SAMSN1 genes in Kasumi-1 cells.

• Format:

  Solid

• Molecular Formula:

  C22H22F3N3O3S2

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  At least 6 months at -20°C.

• Calculated Molecular Weight:

  497.6 Da

• CAS Number:

  1714146-59-4