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NI-57

CAT: 0421-82069Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0421-82069Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NI-57 is a selective and potent inhibitor of BRPF (Bromodomain and PHD Finger) family of proteins (BRPF1/2/3) . NI-57 shows Kd values of 31,108 and 408 nM, for BRPF1B, 2 and 3, respectively. NI-57 also exhibits >32-fold selectivity for BRPFs over BRD9 and other non-Class IV bromodomains. Inhibits RANKL-induced differentiation of primary murine bone marrow cells and human primary monocytes into osteoclasts.
CAS Number
1883548-89-7
Format
Solid
Molecular Formula
C19H17N3O4
Shipping Conditions
Room Temperature
Storage Conditions
At least 6 months at -20°C.
Calculated Molecular Weight
383.4 Da

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