Altretamine

• Description:

  Altretamine is an alkylating antineoplastic agent.

• Product Name Alternative:

  ENT-50852; RB-1515; WR-95704

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  DNA Alkylator/Crosslinker

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/Altretamine.html

• Purity:

  99.94

• Solubility:

  DMSO : 8.33 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL

• Smiles:

  CN(C)C1=NC(N(C)C)=NC(N(C)C)=N1

• Molecular Formula:

  C9H18N6

• Molecular Weight:

  210.28

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Kelner MJ, et al. Synergy of irofulven in combination with other DNA damaging agents: synergistic interaction with altretamine, alkylating, and platinum-derived agents in the MV522 lung tumor model. Cancer Chemother Pharmacol. 2008 Dec;63 (1) :19-26.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  Launched

• CAS Number:

  [645-05-6]