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CHO/Human CD16a (158V) Stable Cell Line (Medium Expression)

CAT: 0716-SCCHO-ATP059M-2VialsSize: 2 VialsDry Ice: YesHazardous: No
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CAT#:0716-SCCHO-ATP059M-2VialsSize:2 Vials
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CD16 is a low affinity Fc receptor, and has been identified as Fc receptors FcγRIIIa (CD16a) and FcγRIIIb (CD16b) . These receptors bind to the Fc portion of IgG antibodies. CD16 encoded by two different highly homologous genes in a cell type-specific manner.CD16 is found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages. CD16a antigen is also known as Low affinity immunoglobulin gamma Fc region receptor III-A, Fc-gamma RIII-alpha. CD16b is a low-affinity, GPI-linked receptor expressed by neutrophils and eosinophils, whereas CD16a is an intermediate affinity polypeptide-anchored transmembrane glycoprotein expressed natural killer cells, macrophages, subpopulation of T-cells, immature thymocytes and placentaltrophoblasts.CD16a is involved in phagocytosis, secretion of enzymes and inflammatory mediators, antibody­dependent cytotoxicity and clearance of immune complexes. Aberrant expression or mutations of CD16a is implicated in susceptibility to recurrent viral infections, systemic lupus erythematosus, and alloimmune neonatal neutropenia.
Description
CHO/Human CD16a (158V) Stable Cell Line (Medium Expression) is expressed from Human CHO.
Host
CHO
Origin Species
Human
Target
Fc gamma RIIIA / CD16a
Applications
• Useful for cell-based CD16a (158V) binding assay • Useful for CD16a (158V) -mediated crosslinking
Format
Liquid
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
Dry ice
Storage Conditions
Frozen in liquid nitrogen
Package Size
1Vial*2
Host or Source
CHO
Species
Human

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