Noggin

• Accession Number:

  Q13253

• Expression Region:

  Gln28-Cys232

• Expression System:

  CHO

• Tag:

  Tag free

• Stability:

  36 months at -20°C to -80°C in lyophilized state 6 months at -20°C to -80°C under sterile conditions after reconstitution 7-10 days at 2°C to 8°C under sterile conditions after reconstitution Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

• Endotoxin:

  ≤10 EU/mg

• Purity:

  ≥ 95% as determined by SDS-PAGE

• Activity:

  Derermined by its abitity to inhibit 5.0 ng/ml of BMP-4 induced alkaline phosphatase production by ATDC-5 chondrogenic cells. The ED50 for this effect is 2.0-3.0 ng/mL of Noggin.

• Reconstitution:

  It is recommended to redissolve in sterile deionized water

• Molecular Weight:

  23 kDa

• Shipping Conditions:

  Blue Ice

• Appearance:

  White powder, Colorless clear liquid after reconstitution

• Formulation:

  Lyophilized from a 0.22 μm-filtered solution containing PBS, 5% mannitol and 0.01% Tween 80, pH 7.4

• Product Name Synonym:

  Noggin; NOG

• Species:

  Human