Products for Research Use Only

Gum arabic

CAT: 0804-HY-N6664-01Size: 10 gDry Ice: NoHazardous: No
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CAT#:0804-HY-N6664-01Size:10 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Gum Arabic is an orally active complex branched polysaccharide. Gum Arabic can be isolated from the Acacia senegal tree. Gum Arabic upregulates the expression of maturation markers (CD86, CD40, and CD54), promotes ERK1/2 phosphorylation, and inhibits Apoptosis. Gum Arabic exhibits antimalarial effects against Plasmodium berghei ANKA. Gum Arabic exhibits hepatoprotective, renal, and cardiovascular protective activities. Gum Arabic improves obesity. Gum Arabic is commonly used as a stabilizer and thickener. Gum Arabic can be used in the research of brain tumor imaging[1][2][3][4][5][6][7][8][9][10].
CAS Number
9000-01-5
Product Name Alternative
Arabic gum
UNSPSC
12352005
Hazard Statement
H315-H319-H335
Target
Apoptosis; Others; Parasite; PERK; Transmembrane Glycoprotein
Type
Natural Products
Related Pathways
Anti-infection; Apoptosis; Cell Cycle/DNA Damage; Immunology/Inflammation; Others
Field of Research
Cancer; Infection; Metabolic Disease; Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/gum-arabic.html
Solubility
H2O : ≥ 50 mg/mL
Smiles
[Gumarabic]
Molecular Weight
200-300
Precautions
P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501
References & Citations
[1]Protective effect of arabic gum against acetaminophen-induced hepatotoxicity in mice. Pharmacological Research. Volume 48, Issue 6, December 2003, Pages 631-635.|[2]Ali BH , et al. Biological effects of gum arabic: a review of some recent research. Food Chem Toxicol. 2009 Jan;47 (1) :1-8.|[3]Gilerovitch HG, et al. The use of electron microscopic immunocytochemistry with silver-enhanced 1.4-nm gold particles to localize GAD in the cerebellar nuclei. J Histochem Cytochem. 1995 Mar;43 (3) :337-43.|[4]Anderson D M W, et al. The safety of gum arabic as a food additive and its energy value as an ingredient: a brief review. Journal of Human Nutrition and Dietetics, 1989, 2 (3) : 137-144.|[5]Ballal A, et al. Anti-malarial effect of gum arabic. Malar J. 2011 May 20;10:139. |[6]Xuan NT, et al. Stimulation of mouse dendritic cells by Gum Arabic. Cell Physiol Biochem. 2010;25 (6) :641-8.|[7]Zhang L, et al. Gum arabic-coated magnetic nanoparticles for potential application in simultaneous magnetic targeting and tumor imaging. AAPS J. 2009 Dec;11 (4) :693-9. |[8]Ali BH, et al. Gum arabic reduces inflammation, oxidative, and nitrosative stress in the gastrointestinal tract of mice with chronic kidney disease. Naunyn Schmiedebergs Arch Pharmacol. 2020 Aug;393 (8) :1427-1436. |[9]Nemmar A, et al. Gum Arabic Ameliorates Impaired Coagulation and Cardiotoxicity Induced by Water-Pipe Smoke Exposure in Mice. Front Physiol. 2019 Feb 25;10:53. |[10]Ahmed A A, et al. Gum arabic suppressed diet-induced obesity by alteration the expression of mRNA levels of genes involved in lipid metabolism in mouse liver. Bioactive carbohydrates and dietary fibre, 2016, 7 (1) : 15-20.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported