4-MUNANA

• Description:

  4-MUNANA is a substrate of influenza virus neuraminidase (NA) with high selectivity and irreversible reaction. In the enzymatic reaction, 4-MUNANA is hydrolyzed by NA to generate fluorescent 4-methylumbelliferone (4-MU) . By detecting the fluorescence intensity of 4-MU, quantitative analysis of NA activity can be achieved. 4-MUNANA can be used in influenza-related research, such as screening NA inhibitors, developing new anti-influenza drugs, and studying the infection mechanism of influenza viruses[1][2].

• UNSPSC:

  12171500

• Hazard Statement:

  H315, H319, H335

• Target:

  Fluorescent Dye

• Type:

  Dye Reagents

• Related Pathways:

  Others

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection; Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/4-munana.html

• Purity:

  98.08

• Solubility:

  H2O : 233.33 mg/mL (ultrasonic)

• Smiles:

  O=C (O[Na]) [C@@]1 (O[C@@] ([C@@H] ([C@H] (C1) O) NC (C) =O) ([H]) [C@H] (O) [C@H] (O) CO) OC2=CC=C (C (C) =CC (O3) =O) C3=C2

• Molecular Formula:

  C21H24NNaO11

• Molecular Weight:

  489.41

• Precautions:

  H315, H319, H335

• References & Citations:

  [1]Xu R, et al. Functional balance of the hemagglutinin and neuraminidase activities accompanies the emergence of the 2009 H1N1 influenza pandemic. J Virol. 2012 Sep;86 (17) :9221-32.|[2]Ma F, et al. Fluorescence paper sensor meets magnetic affinity chromatography: discovering potent neuraminidase inhibitors in herbal medicines. Anal Bioanal Chem. 2025 Apr;417 (9) :1819-1832.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, sealed storage, away from moisture and light)

• Scientific Category:

  Dye Reagents

• Clinical Information:

  No Development Reported

• CAS Number:

  76204-02-9