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Ganoderic acid C2

CAT:
804-HY-N1517-02
Size:
10 mg
Price:
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  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
Ganoderic acid C2 - image 1

Ganoderic acid C2

  • CAS Number: 103773-62-2
  • UNSPSC Description: Ganoderic acid C2 is a bioactive triterpenoid in Ganoderma lucidum. Ganoderic acid C2 possesses the potential anti-tumor bioactivity, antihistamine, anti-aging and cytotoxic effects. Ganoderic acid C2 exhibits high inhibitory activity against the rat lens aldose reductase (RLAR) with an IC50 of 3.8 µM[1][2].
  • Target Antigen: Aldose Reductase
  • Type: Natural Products
  • Related Pathways: Metabolic Enzyme/Protease
  • Applications: Cancer-programmed cell death
  • Field of Research: Cancer
  • Assay Protocol: https://www.medchemexpress.com/ganoderic-acid-c-2.html
  • Purity: 99.30
  • Solubility: DMSO : 50 mg/mL (ultrasonic)
  • Smiles: CC1(C)[C@@H](O)CC[C@]2(C)C3=C([C@@]4([C@@H](O)C[C@@H]([C@]4(CC3=O)C)[C@H](C)CC(C[C@@H](C)C(O)=O)=O)C)[C@@H](O)C[C@@]12[H]
  • Molecular Weight: 518.68
  • References & Citations: [1]Guo XY, et al. l characterization of minor metabolites and pharmacokinetics of ganoderic acid C2 in rat plasma by HPLC coupled with electrospray ionization tandem mass spectrometry. J Pharm Biomed Anal. 2013 Mar 5;75:64-73.|[2]Fatmawati S, et al. Inhibition of aldose reductase in vitro by constituents of Ganoderma lucidum. Planta Med. 2010 Oct;76(15):1691-3.
  • Shipping Conditions: Room Temperature
  • Storage Conditions: 4°C (Powder, protect from light)
  • Clinical Information: No Development Reported