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Zervimesine

CAT: 0804-HY-111669-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-111669-01Size:5 mg
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Description
Zervimesine (CT1812) is an orally active and brain penetrant sigma-2 receptor antagonist with a Ki of 8.5 nM. Zervimesine can be used for the research of Alzheimer’s disease[1].
CAS Number
1802632-22-9
Product Name Alternative
CT1812; Sigma-2 receptor antagonist 1
UNSPSC
12352005
Target
Sigma Receptor
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ct1812.html
Purity
99.01
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC1=CC=C(CCC(C)(N2CC3=C(C=C(S(=O)(C)=O)C=C3)C2)C)C=C1OC(C)(C)C
Molecular Formula
C24H33NO4S
Molecular Weight
431.59
References & Citations
[1]Izzo NJ, et al. Preclinical and clinical biomarker studies of CT1812: A novel approach to Alzheimer's disease modification. Alzheimers Dement. 2021 Aug;17 (8) :1365-1382.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
Sigma 2 Receptor

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