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Box5

CAT: 0804-HY-123071-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-123071-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Box5 is a potent Wnt5a antagonist. Box5 inhibits Wnt5a signaling and inhibits Wnt5a-mediated Ca2+ release. Box5 inhibits cell migration. Box5 has the potential for the research of melanoma[1].
CAS Number
[1206604-29-6]
UNSPSC
12352209
Target
Wnt
Type
Peptides
Related Pathways
Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/box5.html
Purity
99.24
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(C)C[C@@H](C(O)=O)NC([C@H](CCC(O)=O)NC([C@H](CS)NC(CNC([C@H](CC(O)=O)NC([C@H](CCSC)NC(OC(C)(C)C)=O)=O)=O)=O)=O)=O
Molecular Formula
C30H50N6O13S2
Molecular Weight
766.88
References & Citations
[1]Jenei V, et al. A t-butyloxycarbonyl-modified Wnt5a-derived hexapeptide functions as a potent antagonist of Wnt5a-dependent melanoma cell invasion. Proc Natl Acad Sci U S A. 2009 Nov 17;106 (46) :19473-8.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
Wnt5
Citation 01
J Mol Cell Biol. 2025 Jul 28;17 (2) :mjaf002.|J Neuroinflammation. 2024 Mar 26;21 (1) :75.|J Transl Med. 2025 Mar 6;23 (1) :282.|Nano Today. 2024 Apr, 55, 102201.|Adv Sci (Weinh) . 2025 Jun 24:e02774.|J Immunother Cancer. 2025 Mar 22;13 (3) :e010555.|Oral Dis. 2024 May 8.

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