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Eprosartan

CAT: 0804-HY-117743-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-117743-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Eprosartan (SKF-108566J free base) is a selective, competitive, nonpeptid and orally active angiotensin II receptor antagonist, used as an antihypertensive. Eprosartan binds angiotensin II receptor with IC50s of 9.2 nM and 3.9 nM in rat and human adrenal cortical membranes, respectively [1].
CAS Number
133040-01-4
Product Name Alternative
SKF-108566J (free base)
UNSPSC
12352005
Hazard Statement
H315, H319
Target
Angiotensin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/eprosartan.html
Purity
99.87
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=C(C=C1)CN2C(/C=C(CC3=CC=CS3)/C(O)=O)=CN=C2CCCC)O
Molecular Formula
C23H24N2O4S
Molecular Weight
424.51
Precautions
H315, H319
References & Citations
[1]R M Edwards, et al. Pharmacological characterization of the nonpeptide angiotensin II receptor antagonist, SK&F 108566. J Pharmacol Exp Ther. 1992 Jan;260 (1) :175-81.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Citation 01
ACS Environ Au. 2025 Aug 8.|Anal Chem. 2025 Jun 3;97 (21) :11099-11109.|J Lumin. 2018 Nov; 203;616-628.

Alternative Products

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274986-01Eprosartan
B1746-5.1Eprosartan Mesylate

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