resDetect™ VH3 ELISA Kit (Residue Testing)

resDetect™ VH3 ELISA Kit (Residue Testing)

• Background: Traditional protein A have affinity for both the Fc region and the Fab VH3 region of human antibodies. But VH3 interacts only with the variable heavy chain of the VH3 sequence family of the human antibody，it can be widely used in the purification of related antibody drugs.. However, during the purification , VH3 may leach from the purification column and resulte in contamination of the antibody drugs prepared. Therefore, the detection of residual VH3 in antibody drugs purified from VH3 purification column is a key quality control step in the production process of antibody drug preparations.
• Description: Traditional protein A have affinity for both the Fc region and the Fab VH3 region of human antibodies. But VH3 interacts only with the variable heavy chain of the VH3 sequence family of the human antibody，it can be widely used in the purification of related antibody drugs.. However, during the purification , VH3 may leach from the purification column and resulte in contamination of the antibody drugs prepared. Therefore, the detection of residual VH3 in antibody drugs purified from VH3 purification column is a key quality control step in the production process of antibody drug preparations.
• CAS Number: 7732-18-5
• Target: VH3
• Applications: The kit is developed for the detection of natural or structurally conserved recombinant forms of VH3 and a recombinant form of VH3 with very significant structural differences from natural VH3 such as MabSelect VH3 in Bioprocess manufacturing applications. It is used as a tool to aid in optimal purification process development and in routine quality control of in-process streams as well as final product .
• Stability: 1. Unopened kit should be stored at 2°C-8°C upon receiving. 2. Find the expiration date on the outside packaging and do not use reagents past their expiration date. 3. The opened kit should be stored per components table. The shelf life is 30 days from the date of opening.
• Format: Solid
• Shipping Conditions: Room Temperature
• Storage Conditions: 2-8°C