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C12-NBD Sphinganine

CAT: 0804-HY-141577-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-141577-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
C12-NBD Sphinganine is a fluorescent ceramidase substrate. C12-NBD Sphinganine can be used for the measurement of alkaline and neutral ceramidase activity from a variety of sources[1][2][3].
CAS Number
474943-05-0
UNSPSC
12171500
Target
Biochemical Assay Reagents
Type
Dye Reagents
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/c12-nbd-sphinganine.html
Purity
99.9
Solubility
10 mM in DMSO
Smiles
CCCCCCCCCCCCCCC[C@@H](O)[C@H](CO)NC(CCCCCCCCCCCNC1=CC=C([N+]([O-])=O)C2=NON=C12)=O
Molecular Formula
C36H63N5O6
Molecular Weight
661.92
References & Citations
[1]Rigogliuso S, et al. An active form of sphingosine kinase-1 is released in the extracellular medium as component of membrane vesicles shed by two human tumor cell lines. J Oncol. 2010;2010:509329.|[2]Okino N, et al. Expression, purification, and characterization of a recombinant neutral ceramidase from Mycobacterium tuberculosis. Biosci Biotechnol Biochem. 2010;74 (2) :316-21.|[3]Vijai Kumar Reddy T, et al. Design, synthesis and in vitro biological evaluation of short-chain C12-sphinganine and its 1,2,3-triazole analogs as potential antimicrobial and anti-biofilm agents. Eur J Med Chem. 2016 Aug 8;118:98-106.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Dye Reagents
Clinical Information
No Development Reported

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