Prednisolone

• UNSPSC Description:

  Prednisolone is a potent, orally active corticosteroid and a glucocorticoid. Prednisolone possesses about four times the anti-inflammatory activity of hydrocortisone while causing less salt and water retention. Prednisolone can be used for ocular, anti-inflammatory research[1][2].

• Target Antigen:

  Endogenous Metabolite; Glucocorticoid Receptor

• Type:

  Natural Products

• Related Pathways:

  Immunology/Inflammation;Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor

• Field of Research:

  Endocrinology; Inflammation/Immunology; Cancer

• Assay Protocol:

  https://www.medchemexpress.com/Prednisolone.html

• Solubility:

  DMSO : 62.5 mg/mL (ultrasonic)|H2O : 0.1 mg/mL (ultrasonic)

• Smiles:

  C[C@@]1([C@@]2(O)C(CO)=O)[C@](CC2)([H])[C@@](CCC3=CC4=O)([H])[C@]([C@]3(C=C4)C)([H])[C@@H](O)C1

• Molecular Weight:

  360.44

• References & Citations:

  [1]Prednisolone. J Am Pharm Assoc. 1976;16(3):143-146.|[2]Musson DG, et al. Assay methodology for prednisolone, prednisolone acetate and prednisolone sodium phosphate in rabbit aqueous humor and ocular physiological solutions. J Chromatogr. 1991;565(1-2):89-102.|[3]Hahn B H, et al. Comparison of therapeutic and immunosuppressive effects of azathioprine, prednisolone and combined therapy in nzp/nzw mice. Arthritis & Rheumatism: Official Journal of the American College of Rheumatology, 1973, 16(2): 163-170.|[4]NOWELL PC. Inhibition of human leukocyte mitosis by prednisolone in vitro. Cancer Res. 1961 Dec;21:1518-21.

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  Launched

• CAS Number:

  50-24-8