Methyl cholate

CAT: 0804-HY-107830-01Size: 100 mgDry Ice: NoHazardous: No
CAT#:0804-HY-107830-01Size:100 mg
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Description
Methyl cholate is a methyl ester of bile acid and sterol esters that can act as supramolecular carriers for aldoses (e.g., glucose, galactose, mannose) . Methyl cholate selectively binds to aldoses to form non-covalent complexes and migrates in supported liquid membranes (SLMs), thereby facilitating the transport of sugars. Cholic acid is one of the major bile acids produced by the liver and is synthesized from cholesterol. Methyl cholate can be used to study the selective separation and transport of carbohydrates[1][2][3].
CAS Number
[1448-36-8]
UNSPSC
12352211
Hazard Statement
H315, H319, H320
Target
Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/methyl-cholate.html
Concentration
10mM
Purity
99.81
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O[C@H]1[C@@]2([H])[C@@]3([H])[C@@]([C@]([C@H](C)CCC(OC)=O)([H])CC3)([C@@H](O)C[C@]2([H])[C@]4(C)[C@](C[C@H](O)CC4)([H])C1)C
Molecular Formula
C25H42O5
Molecular Weight
422.60
Precautions
H315, H319, H320
References & Citations
[1]Al-Aboudi A, et al. Biotransformation of methyl cholate by Aspergillus niger. Steroids. 2009 Apr-May;74 (4-5) :483-6.|[2]L J Bennion, et al. Effects of Oral Contraceptives on the Gallbladder Bile of Normal Women. N Engl J Med, 294 (4), 189-92 1976 Jan 22|[3]Hassoune H, et al. Mechanism of transport of sugars across a supported liquid membrane using methyl cholate as mobile carrier[J]. Desalination, 2009, 242 (1-3) : 84-95.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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