Biotin-Cel

• Description:

  Biotin-Cel (Celastrol-Biotin) is a biotin-labeled Celastrol (HY-13067) . Celastrol exhibits antitumor, anti-inflammatory, and anti-obesity activities. Biotin-Cel can be used in biotin-affinity pulldown assay to identify the molecular target of Celastrol in hepatocellular carcinoma cells[1].

• Product Name Alternative:

  Celastrol-Biotin

• UNSPSC:

  12352005

• Target:

  Biochemical Assay Reagents

• Type:

  Reference compound

• Related Pathways:

  Others

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/biotin-cel.html

• Purity:

  96.49

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  C[C@@]12[C@]([C@@]3([H])[C@@](CC1)(CC[C@](C)(C3)C(NCCNC(CCCC[C@H]4[C@]5([H])[C@](NC(N5)=O)([H])CS4)=O)=O)C)(CC[C@@]6(C2=CC=C7C6=CC(C(O)=C7C)=O)C)C

• Molecular Formula:

  C41H58N4O5S

• Molecular Weight:

  718.99

• References & Citations:

  [1]Du S, et al., Celastrol inhibits ezrin-mediated migration of hepatocellular carcinoma cells. Sci Rep. 2020 Jul 9;10 (1) :11273.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [2609685-71-2]