Biotin-Cel

• Description :

  Biotin-Cel (Celastrol-Biotin) is a biotin-labeled Celastrol (HY-13067) . Celastrol exhibits antitumor, anti-inflammatory, and anti-obesity activities. Biotin-Cel can be used in biotin-affinity pulldown assay to identify the molecular target of Celastrol in hepatocellular carcinoma cells[1].

• CAS Number :

  [2609685-71-2]

• Product Name Alternative :

  Celastrol-Biotin

• UNSPSC :

  12352005

• Target :

  Biochemical Assay Reagents

• Type :

  Reference compound

• Related Pathways :

  Others

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/biotin-cel.html

• Purity :

  96.49

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  C[C@@]12[C@]([C@@]3([H])[C@@](CC1)(CC[C@](C)(C3)C(NCCNC(CCCC[C@H]4[C@]5([H])[C@](NC(N5)=O)([H])CS4)=O)=O)C)(CC[C@@]6(C2=CC=C7C6=CC(C(O)=C7C)=O)C)C

• Molecular Formula :

  C41H58N4O5S

• Molecular Weight :

  718.99

• References & Citations :

  [1]Du S, et al., Celastrol inhibits ezrin-mediated migration of hepatocellular carcinoma cells. Sci Rep. 2020 Jul 9;10 (1) :11273.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported