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Sapurimycin

CAT: 0804-HY-117818Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-117818Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Sapurimycin is an antitumor antibiotic isolated from Streptomyces DO-116 and belongs to the capramycin family. Sapurimycin exhibits potent activity against Gram-positive bacteria and exhibits significant antitumor effects against leukemia P388 and sarcoma 180 in mouse models. In vitro studies have shown that Sapurimycin can induce single-strand breaks in supercoiled plasmid DNA[1].
CAS Number
132609-35-9
Product Name Alternative
Antibiotic DC 116
UNSPSC
12352005
Target
Antibiotic
Type
Natural Products
Related Pathways
Anti-infection
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sapurimycin.html
Smiles
O=C(O)CC(C=C1C(C2=C3C(O)=CC=C2O)=O)=C(C(C=C([C@@]4(C)O[C@H]4/C=C\C)O5)=O)C5=C1C3=O
Molecular Formula
C25H18O9
Molecular Weight
462.41
References & Citations
[1]PURIMYCIN, NEW ANTITUMOR ANTIBIOTIC PRODUCED BY STREPTOMYCES PRODUCING ORGANISM, FERMENTATION, ISOLATION AND BIOLOGICAL PROPERTIES
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

Alternative Products

CatalogName
TN11228-01Sapurimycin

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