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Emicerfont

CAT: 0804-HY-14367-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-14367-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Emicerfont is a corticotropin-releasing factor type 1 (CRF1) receptor antagonist with an IC50 of 66 nM.
CAS Number
786701-13-1
Product Name Alternative
GW876008
UNSPSC
12352005
Target
CRFR
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Neurological Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/Emicerfont.html
Purity
98.03
Smiles
CC1=CC(OC)=CC=C1N(CC2)C3=C2C(N4C=CC(N5CCN([H])C5=O)=N4)=CC(C)=N3
Molecular Formula
C22H24N6O2
Molecular Weight
404.46
References & Citations
[1]Zorrilla EP, et al. Behavioral, biological, and chemical perspectives on targeting CRF (1) receptor antagonists to treat alcoholism. Drug Alcohol Depend. 2013 Mar 1;128 (3) :175-86.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
Phase 2

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T15214-01Emicerfont
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A14047-50Emicerfont 50mg
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A14047-10Emicerfont 10mg
A14047-5Emicerfont 5mg

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