Bisdemethoxycurcumin

CAT: 0026-B2944-250Size: 250 mgDry Ice: NoHazardous: No
CAT#:0026-B2944-250Size:250 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Bisdemethoxycurcumin is a curcumin analogue with anti-inflammatory and anti-proliferative properties. It suppresses tumor necrosis factor (TNF)-induced nuclear factor-kappaB (NF-kappaB) activation in KBM-5 cells and inhibits proliferation of different cell lines at 25 μM. Bisdemethoxycurcumin enhances phagocytosis of amyloid-beta and transcription of MGAT3 and TLR. It down-regulates the transcriptional coactivator p300 and thereby inhibits the Wnt/beta-catenin pathway. It inhibits inducible nitric oxide synthase protein expression and accelerates healing of gastric ulcer in a rat model.
Shipping Conditions
RT
Storage Conditions
-20ºC
Shelf Life
36months

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