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HZ1

CAT: 0804-HY-161847-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-161847-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Anticancer agent 241 (HZ1) is an orally active first-in-class cyclin-dependent kinase like 3 (CDKL3) -specific inhibitor. Anticancer agent 241 shows a strong tumor-suppressing effect, and has the potential to overcome the resistance of CDK4/6 inhibitor[1].
CAS Number
3030492-40-8
UNSPSC
12352005
Target
Ser/Thr Protease
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hz1.html
Purity
99.20
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(C)C(C=C1)=CC=C1NC2=NC(NC3=CC(C4CCCC4)=NN3)=CC=N2
Molecular Formula
C20H22N6O
Molecular Weight
362.43
References & Citations
[1]Haijiao Zhang, et al. CDKL3 is a targetable regulator of cell cycle progression in cancers. J Clin Invest. 2024 Jul 4:e178428.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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