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Cinobufaginol

CAT: 0804-HY-N7020Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N7020Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cinobufaginol is a natural bufadienolide isolated from toad venom which has been widely used for centuries in China to treat different diseases, especially for cancer. Cinobufaginol potently inhibits the activity against human nasopharyngeal carcinoma cell lines with IC50s of 803 μΜ and 1.270 μΜ for CNE-1 and CNE-2Z, respectively[1].
CAS Number
6691-83-4
UNSPSC
12352005
Target
Others
Type
Natural Products
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cinobufaginol.html
Purity
99.75
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(C=C1)OC=C1[C@H]2[C@@H](OC(C)=O)[C@@]3([H])[C@]4(O3)[C@]5([H])CC[C@]6([H])C[C@@H](O)CC[C@]6(CO)[C@@]5([H])CC[C@]24C
Molecular Formula
C26H34O7
Molecular Weight
458.54
References & Citations
[1]Liu JS, et al. Anti-tumor effects and 3D-quantitative structure-activity relationship analysis of bufadienolidesfrom toad venom. Fitoterapia. 2019 Apr;134:362-371.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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