4-Hydroxymethylpyrazole

• UNSPSC Description:

  4-Hydroxymethylpyrazole is the primary metabolite of Fomepizole (HY-B0876). Fomepizole is a competitive inhibitor of the enzyme alcohol dehydrogenase[1].

• Target Antigen:

  Drug Metabolite; Endogenous Metabolite

• Type:

  Natural Products

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/4-hydroxymethylpyrazole.html

• Purity:

  99.97

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)|H2O : 100 mg/mL (ultrasonic)

• Smiles:

  OCC1=CNN=C1

• Molecular Weight:

  98.105

• References & Citations:

  [1]R Blomstrand, et al. Pyrazoles as Inhibitors of Alcohol Oxidation and as Important Tools in Alcohol Research: An Approach to Therapy Against Methanol Poisoning. Proc Natl Acad Sci U S A . 1979 Jul;76(7):3499-503.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  25222-43-9