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Asebogenin

CAT: 0804-HY-N7314-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N7314-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Asebogenin has antimalarial activity in vitro[1]. Asebogenin can inhibit the phosphorylation of Syk, thereby effectively suppressing platelet activation and the formation of neutrophil extracellular traps[2].
CAS Number
520-42-3
UNSPSC
12352005
Target
Syk
Type
Natural Products
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/asebogenin.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C(O)C=C(OC)C=C1O)CCC2=CC=C(O)C=C2
Molecular Formula
C16H16O5
Molecular Weight
288.30
References & Citations
[1]1.Jenett-Siems K, et al. n vitro antiplasmodial activity of Central American medicinal plants. Trop Med Int Health. 1999 Sep;4 (9) :611-5. |[2]Li L, et al. Asebogenin suppresses thrombus formation via inhibition of Syk phosphorylation. Br J Pharmacol. 2023 Feb;180 (3) :287-307.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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CatalogName
BUP20752-01Asebogenin

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