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Vicine

CAT: 0804-HY-N2093-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N2093-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Vicine, an alkaloid glycoside found mainly in fava beans, is toxic in individuals who have a hereditary loss of the enzyme glucose-6-phosphate dehydrogenase and may cause haemolytic anaemia.Vicine is an inactive compound that is hydrolysed by the intestinal microflora to a highly reactive free radical generating compound, the aglycone divicine when Vicine enters the body through food[1][2][3][4].
CAS Number
152-93-2
UNSPSC
12352005
Hazard Statement
H302
Target
Drug Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/vicine.html
Purity
99.79
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C1N=C(N)NC(N)=C1O[C@H]2[C@@H]([C@H]([C@@H]([C@@H](CO)O2)O)O)O
Molecular Formula
C10H16N4O7
Molecular Weight
304.26
Precautions
H302
References & Citations
[1]Farran MT, et al. Vicine and convicine in common vetch (Vicia sativa) seeds enhance beta-cyanoalanine toxicity in male broiler chicks. Int J Toxicol. 2002 May-Jun;21 (3) :201-9.|[2]Lattanzio V, et al. Variability of amino acids, protein, vicine and convicine in Vicia faba (L) cultivars[J]. Journal of Food Science, 1983, 48 (3) : 992-993.|[3]Liener IE. Toxic constituents of plant foodstuffs. Proc Nutr Soc. 1970 May;29 (1) :56-7. |[4]Khazaei H, et al. Eliminating vicine and convicine, the main anti-nutritional factors restricting faba bean usage[J]. Trends in Food Science & Technology, 2019, 91: 549-556.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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