Human Factor XIIa Beta

• UNSPSC Description:

  Human Factor XIIa Beta is the active fragment of coagulation factor XII, that participates in the intrinsic pathway of coagulation, and leads to the formation of blood clots. Human Factor XIIa Beta also participates in the kinin-generating pathway, which leads to the release of bradykinin (vasodilator). Human Factor XIIa Beta stimulates the release of catecholamines, and mediates its cardiovascular effects through a noncholinergic angiotensin-converting enzyme (ACE)-regulated mechanism[1].

• Target Antigen:

  Angiotensin Receptor

• Type:

  Enzyme

• Related Pathways:

  GPCR/G Protein

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/human-factor-xiia-beta.html

• Smiles:

  [Human Factor XIIa Beta]

• References & Citations:

  [1]Papageorgiou PC, et al., Angiotensin converting enzyme-regulated, noncholinergic sympathoadrenal catecholamine release mediates the cardiovascular actions of human 'new pressor protein' related to coagulation beta-factor XIIa. Can J Cardiol. 2009 Apr;25(4):e100-8

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported