Picotamide

• Description:

  Picotamide is a combined inhibitor of thromboxane A2 (TxA2) synthase and receptor. Picotamide has antiplatelet activity. Picotamide promotes the reduction of microalbuminuria and the inhibition of growth of carotid plaques in diabetes. Picotamide can be used for researching acute or chronic cardiovascular diseases[1].

• UNSPSC:

  12352005

• Hazard Statement:

  H315, H319

• Target:

  Prostaglandin Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/picotamide.html

• Purity:

  99.76

• Solubility:

  DMSO : 5 mg/mL (ultrasonic; warming)

• Smiles:

  O=C(C1=CC=C(OC)C(C(NCC2=CC=CN=C2)=O)=C1)NCC3=CC=CN=C3

• Molecular Formula:

  C21H20N4O3

• Molecular Weight:

  376.41

• Precautions:

  H315, H319

• References & Citations:

  [1]Celestini A, et al. A review of picotamide in the reduction of cardiovascular events in diabetic patients. Vasc Health Risk Manag. 2007;3 (1) :93-98.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  TXA2/TP

• CAS Number:

  [32828-81-2]