1-Stearoyl-2-oleoyl-sn-glycerol-3-phosphoethanolamine

1-Stearoyl-2-oleoyl-sn-glycerol-3-phosphoethanolamine

• CAS Number: 6418-95-7
• UNSPSC Description: 1-Stearoyl-2-oleoyl-sn-glycerol-3-phosphoethanolamine is a phospholipids that contains stearic acid and oleic acid at the sn-1 and sn-2 positions, respectively. It has been used in the generation of lipid nanoparticles (LNPs) for in vitro delivery of mRNA or nuclear-targeted plasmid DNA.
• Target Antigen: Liposome
• Type: Biochemical Assay Reagents
• Related Pathways: Metabolic Enzyme/Protease
• Field of Research: Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/1-stearoyl-2-oleoyl-sn-glycerol-3-phosphoethanolamine.html
• Solubility: 10 mM in DMSO
• Smiles: CCCCCCCC/C=C\CCCCCCCC(O[C@@H](COP(O)(OCCN)=O)COC(CCCCCCCCCCCCCCCCC)=O)=O
• Molecular Weight: 746.05
• References & Citations: [1]Álvarez-Benedicto, E., Farbiak, L., Ramírez, M.M., et al. Optimization of phospholipid chemistry for improved lipid nanoparticle (LNP) delivery of messenger RNA (mRNA). Biomater. Sci. 10(2), 549-559 (2022).|[2]Tanaka, H., Akita, H., Ishiba, R., et al. Neutral biodegradable lipid-envelope-type nanoparticle using vitamin A-Scaffold for nuclear targeting of plasmid DNA. Biomaterials 35(5), 1755-1761 (2014).
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported