STM2120

• Description:

  STM2120 is a METTL3-METTL14 inhibitor with an IC50 of 64.5 μM[1].

• UNSPSC:

  12352005

• Target:

  METTL3

• Type:

  Reference compound

• Related Pathways:

  Epigenetics

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/stm2120.html

• Purity:

  99.92

• Solubility:

  DMSO : 100 mg/mL (ultrasonic; warming; heat to 80°C)

• Smiles:

  O=C1C=C(C(NCC2=CN3C(C)=CC=CC3=N2)=O)N=C4C=CC=CN14

• Molecular Formula:

  C18H15N5O2

• Molecular Weight:

  333.34

• References & Citations:

  [1]Yankova E, et al. Small-molecule inhibition of METTL3 as a strategy against myeloid leukaemia. Nature. 2021 May;593 (7860) :597-601.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [2762286-04-2]