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(1R,3S)-RSL3

CAT:
804-HY-100218B-02
Size:
10 mg
Price:
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  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
(1R,3S)-RSL3 - image 1

(1R,3S)-RSL3

  • CAS Number: 1219810-13-5
  • UNSPSC Description: (1R,3S)-RSL3 is the less active (1R,3S)-enantiomer of RSL3 ((1S,3R)-RSL3). (1R,3S)-RSL3 and RSL3 induce cell death in HT22 wild-type cells with EC50 values of 5.2 µM and 0.004 µM, rspectively[1].
  • Target Antigen: Others
  • Type: Reference compound
  • Related Pathways: Others
  • Applications: Cancer-programmed cell death
  • Field of Research: Cancer
  • Assay Protocol: https://www.medchemexpress.com/1r-3s-rsl3.html
  • Solubility: 10 mM in DMSO
  • Smiles: O=C([C@@H]1CC2=C([C@@H](C3=CC=C(C(OC)=O)C=C3)N1C(CCl)=O)NC4=C2C=CC=C4)OC
  • Molecular Weight: 440.88
  • References & Citations: [1]Shin D, et al. Nrf2 inhibition reverses resistance to GPX4 inhibitor-induced ferroptosis in head and neck cancer. Free Radic Biol Med. 2018 Dec;129:454-462.
  • Shipping Conditions: Room temperature
  • Clinical Information: No Development Reported