C6 D-Threo Ceramide (d18:1/6:0)

C6 D-Threo Ceramide (d18:1/6:0)

• CAS Number: 189894-79-9
• UNSPSC Description: C6 D-Threo Ceramide (d18:1/6:0) is a bioactive sphingolipid and cell-permeable analog of ceramides. C6 D-Threo Ceramide (d18:1/6:0) enhances IL-4 production induced by Phorbol 12-myristate 13-acetate (HY-18739) in EL4 T cells[1][2].
• Target Antigen: Interleukin Related; Liposome
• Type: Reference compound
• Related Pathways: Immunology/Inflammation;Metabolic Enzyme/Protease
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/c6-d-threo-ceramide-d18-1-6-0.html
• Smiles: OC[C@@H](NC(CCCCC)=O)[C@@H](/C=C/CCCCCCCCCCCCC)O
• Molecular Weight: 397.63
• References & Citations: [1]Park J, et al. Inhibitory activity of a ceramide library on interleukin-4 production from activated T cells. Bioorg Med Chem. 2005 Apr 1;13(7):2589-95.|[2]Irie F, et al. Application of exogenous ceramide to cultured rat spinal motoneurons promotes survival or death by regulation of apoptosis depending on its concentrations. J Neurosci Res. 1998 Nov 15;54(4):475-85.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported