beta Tubulin Recombinant Mouse Monoclonal Antibody [1-B11-R]

beta Tubulin Recombinant Mouse Monoclonal Antibody [1-B11-R]

• Description: Tubulin in molecular biology can refer either to the tubulin protein superfamily of globular proteins, or one of the member proteins of that superfamily. α- and β-tubulins polymerize into microtubules, a major component of the eukaryotic cytoskeleton. Microtubules function in many essential cellular processes, including mitosis. Tubulin-binding drugs kill cancerous cells by inhibiting microtubule dynamics, which are required for DNA segregation and therefore cell division. In eukaryotes, there are six members of the tubulin superfamily, although not all are present in all species. Both α and β tubulins have a mass of around 50 kDa and are thus in a similar range compared to actin (with a mass of ~42 kDa). In contrast, tubulin polymers (microtubules) tend to be much bigger than actin filaments due to their cylindrical nature. Tubulin was long thought to be specific to eukaryotes. More recently, however, several prokaryotic proteins have been shown to be related to tubulin.
• Product Name Alternative: Beta 4 tubulin antibody Beta 5 tubulin antibody BetaTubulin antibody TBB5_HUMAN antibody TUBB antibody TUBB2 antibody TUBB2A antibody TUBB5 antibody tubulin beta 2A antibody Tubulin beta chain antibody Tubulin beta-5 chain antibody
• Abbreviation: TBB5
• CAS Number: 9000-83-3
• Swiss Prot: P07437 Human, P99024 Mouse, P69897 Rat
• Cellular Locus: Cytoplasm ,cytoskeleton
• Host: Mouse
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide within human Beta tubulin aa 51-100.
• Isotype: IgG1
• Clone: 1-B11-R
• Conjugation: Non-conjugated
• Type: Recombinant Mouse monoclonal Antibody
• Applications: WB, IF-Cell, IHC-P
• Positive Control: HeLa cell lysate, MCF7 cell lysate, NCCIT cell lysate, PC-12 cell lysate, F9 cell lysate, NIH/3T3 cell lysate, HeLa, NIH/3T3, human spleen tissue, mouse brain tissue, rat testis tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:5,000 ;IF-Cell: 1:100 ;IHC-P: 1:20
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 50 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: Yes