Trofosfamide

• Description :

  Trofosfamide is an orally bioavailable oxazaphosphorine derivative with antineoplastic activity[1].

• CAS Number :

  [22089-22-1]

• UNSPSC :

  12352005

• Hazard Statement :

  H301, H340, H350, H360, H372, H413

• Target :

  Bacterial

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/trofosfamide.html

• Purity :

  99.66

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  ClCCN1P(OCCC1)(N(CCCl)CCCl)=O

• Molecular Formula :

  C9H18Cl3N2O2P

• Molecular Weight :

  323.58

• Precautions :

  H301, H340, H350, H360, H372, H413

• References & Citations :

  [1]Witte HM, et al. Trofosfamide in the treatment of elderly or frail patients with diffuse large B-cell lymphoma. J Cancer Res Clin Oncol. 2019 Jan;145 (1) :129-136.|[2]Görn M, et al. A pilot study of docetaxel and trofosfamide as second-line 'metronomic' chemotherapy in the treatment of metastatic non-small cell lung cancer (NSCLC) . Onkologie. 2008 Apr;31 (4) :185-9.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  Launched