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Human NOTCH1 recombinant protein

CAT: 0856-PX-P6191-100Size: 100 µgDry Ice: YesHazardous: No
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CAT#:0856-PX-P6191-100Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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UniProt
P46531
Expression System
Eukaryotic expression
Tag
C-Terminal Fc Tag
Type
Recombinant Proteins
Buffer
0.01M PBS, pH 7.4.
Molecular Weight
81.95 kDa
Shipping Conditions
Dry Ice
Storage Conditions
4°C for short term (1 week), -20°C or -80°C for long term (avoid freezing/thawing cycles; addition of 20-40% glycerol improves cryoprotection)
Fragment
Ala19-Gln526
Brand
ProteoGenix
Host or Source
Mammalian cells
Species
Homo sapiens (Human)

UniProtKB · P46531

Neurogenic locus notch homolog protein 1

NOTC1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P46531
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
NOTCH1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
Notch 1, hN1
EC number
—
Processing
Precursor
Secondary accessions
Q59ED8, Q5SXM3
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Molecular function

ActivatorDevelopmental proteinReceptor

Biological process

AngiogenesisDifferentiationNotch signaling pathwayTranscriptionTranscription regulation

Domain

ANK repeatEGF-like domainRepeatSignalTransmembraneTransmembrane helix

Ligand

CalciumMetal-binding

Cellular component

Cell membraneEndosomeMembraneNucleus

Disease

Disease variant

PTM

Disulfide bondGlycoproteinHydroxylationIsopeptide bondPhosphoproteinUbl conjugation

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