Anti-CD3 epsilon (activation epitope) APC

• CAS Number:

  9007-83-4

• Gene Name:

  [CD3E]

• NCBI Gene ID:

  916

• Reactivity:

  Mouse, Human

• Storage Conditions:

  Store in the dark at 2-8 degree C. Do not freeze. Avoid prolonged exposure to light.

• Specificity:

  The mouse monoclonal antibody APA1/1 recognizes an activation-dependent intracellular epitope of CD3 epsilon. Exposure of the epitope precedes CD3 phosphorylation and recruitment and activation of ZAP70, which initiates the signaling cascade produced by T-cell activation. APA1/1 provides the earliest known marker for TCR-mediated T cell activation.

• Other Gene Names:

  [CD3E; CD3E; T3E; TCRE; IMD18; T3E]

• Short Name:

  [CD3 epsilon]

• Other Product Names:

  [T-cell surface glycoprotein CD3 epsilon chain; T-cell surface glycoprotein CD3 epsilon chain; T-cell surface glycoprotein CD3 epsilon chain; CD3e molecule; T-cell surface antigen T3/Leu-4 epsilon chain; CD_antigen: CD3e]

• NCBI GI Number:

  1345708

• NCBI Accession Number:

  P07766.2

• Uniprot Accession Number:

  P07766