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BisSP1

CAT: 0804-HY-147325-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-147325-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BisSP1 is an antibody agent conjugates linker[1]. bisSP1 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
CAS Number
2253947-15-6
UNSPSC
12352203
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/bissp1.html
Purity
95.39
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
[N-]=[N+]=NCCC(N[C@@H](CCCCN)C(NCCCN=[N+]=[N-])=O)=O
Molecular Formula
C12H23N9O2
Molecular Weight
325.37
References & Citations
[1]Kyoji TSUCHIKAMA, et al. Linkers for antibody drug conjugates. Patent WO2018218004A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
ADC Related
Clinical Information
No Development Reported

Chemical Information

bisSP1
CAS Number2253947-15-6
PubChem CID154803551
IUPAC Name(2S)-6-amino-2-(3-azidopropanoylamino)-N-(3-azidopropyl)hexanamide
Molecular FormulaC12H23N9O2
Molecular Weight325.37
XLogP1.2
Topological Polar Surface Area113
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count7
Rotatable Bond Count13
Heavy Atom Count23
Formal Charge0
Complexity455
SMILES
C(CCN)C[C@@H](C(=O)NCCCN=[N+]=[N-])NC(=O)CCN=[N+]=[N-]
InChI
InChI=1S/C12H23N9O2/c13-6-2-1-4-10(19-11(22)5-9-18-21-15)12(23)16-7-3-8-17-20-14/h10H,1-9,13H2,(H,16,23)(H,19,22)/t10-/m0/s1
InChIKey
LRQNLHXWGRMZJY-JTQLQIEISA-N
Chemical Structure
2D Structure
2D structure of bisSP1
CAS: 2253947-15-6
CID: 154803551
Formula: C12H23N9O2
MW: 325.37
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight325.37
XLogP31.2
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count7
Rotatable Bond Count13
Exact Mass325.19747101
Monoisotopic Mass325.19747101
Topological Polar Surface Area113 Ų
Heavy Atom Count23
Formal Charge0
Complexity455
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
BA2410-100bisSP1

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