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Trabikibart

CAT: 0804-HY-P990094-01Size: 1 mgDry Ice: YesHazardous: No
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CAT#:0804-HY-P990094-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Trabikibart (CSL311), a βc (CSF2RB) -specific, fully human monoclonal antibody, binds to a unique epitope that is specific to the cytokine-binding site of the human βc receptor. Trabikibart has picomolar binding affinity for the human βc receptor. Trabikibart is a potent inhibitor of the combined effects of IL-3, GM-CSF and IL-5 on the survival of eosinophils. Trabikibart has the potential for chronic inflammatory diseases research[1].
CAS Number
2643974-98-3
Product Name Alternative
CSL311
UNSPSC
12352203
Target
C-Fms
Type
Inhibitory Antibodies
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/trabikibart.html
Purity
99.17
Solubility
10 mM in DMSO
Smiles
[Trabikibart]
Molecular Weight
(144.66 kDa)
References & Citations
[1]Con Panousis, et al. CSL311, a novel, potent, therapeutic monoclonal antibody for the treatment of diseases mediated by the common β chain of the IL-3, GM-CSF and IL-5 receptors. MAbs. 2016;8 (3) :436-53.
Shipping Conditions
Dry Ice
Storage Conditions
-80°C
Scientific Category
Inhibitory Antibodies
Clinical Information
No Development Reported

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