PI5P4Ks-IN-2

• UNSPSC Description:

  PI5P4Ks-IN-2 is a inhibitor of phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ). PI5P4Ks-IN-2 targets to PI5P4K isoforms with pIC50 values of [1].

• Target Antigen:

  PI5P4K

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/pi5p4ks-in-2.html

• Solubility:

  DMSO : 125 mg/mL (ultrasonic)

• Smiles:

  CN1C=CC2=C1C(NCC3=NC=CC=C3)=NC(C4=CC=CC=C4C(C)C)=N2

• Molecular Weight:

  357.45

• References & Citations:

  [1]Boffey HK, et al. Development of Selective Phosphatidylinositol 5-Phosphate 4-Kinase γ Inhibitors with a Non-ATP-competitive, Allosteric Binding Mode. J Med Chem. 2022 Feb 24;65(4):3359-3370. |[2]Boffey HK, et al. Development of Selective Phosphatidylinositol 5-Phosphate 4-Kinase γ Inhibitors with a Non-ATP-competitive, Allosteric Binding Mode. J Med Chem. 2022 Feb 24;65(4):3359-3370.

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2766854-03-7