DOPE-PEG-DBCO (MW 2000)

• UNSPSC Description:

  DOPE-PEG-DBCO (MW 2000) is a PEG lipid with a DOPE and a DBCO as functional groups. DOPE can be used as a helper lipid in gene transfection. PEG is used in drug delivery system. DBCO can be used for click chemistry[1][2][3].

• Target Antigen:

  Biochemical Assay Reagents

• Type:

  Biochemical Assay Reagents

• Related Pathways:

  Others

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/dope-peg-dbco-mw-2000.html

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  CCCCCCCC/C=C\CCCCCCCC(OC[C@](OC(CCCCCCC/C=C\CCCCCCCC)=O)([H])COP(OCCNC(OCCNC(CCC(N1CC2=C(C=CC=C2)C#CC3=C1C=CC=C3)=O)=O)=O)(O)=O)=O.[n]

• Molecular Weight:

  2000 (Average)

• References & Citations:

  [1]Mochizuki S, et al., The role of the helper lipid dioleoylphosphatidylethanolamine (DOPE) for DNA transfection cooperating with a cationic lipid bearing ethylenediamine. Biochim Biophys Acta. 2013 Feb;1828(2):412-8.|[2]Yoon HI, et al., Bioorthogonal Copper Free Click Chemistry for Labeling and Tracking of Chondrocytes In Vivo. Bioconjug Chem. 2016 Apr 20;27(4):927-36.|[3]D'souza AA, et al., Polyethylene glycol (PEG): a versatile polymer for pharmaceutical applications. Expert Opin Drug Deliv. 2016 Sep;13(9):1257-75.

• Shipping Conditions:

  Blue Ice

• Clinical Information:

  No Development Reported