Biotinylated Anti-SARS-CoV-2 Nucleocapsid Antibody, Chimeric mAb, Human IgG1 (AM223) (MALS verified)

• Background:

  Nucleocapsid (N) protein is the most abundant protein found in coronavirus. CoV N protein is a highly immunogenic phosphoprotein important for viral genome replication and modulation of cell signaling pathways. It was first identified by a research team while they were screening for ADP-ribosylated proteins during coronavirus (CoV) infection (Grunewald M. E., et al. 2017, Virology; 517: 62-68) . The array of diverse functional activities accommodated in N protein makes it more than a structural protein but also an interesting target in the development of antiviral therapeutics. Because of the conservation of N protein sequence and its strong immunogenicity, N protein of coronavirus is chosen as a diagnostic tool.

• Description:

  Biotinylated Anti-SARS-CoV-2 Nucleocapsid Antibody, Chimeric mAb, Human IgG1 (AM223) is a chimeric monoclonal antibody recombinantly expressed from HEK293 cells, which combines the variable region of a mouse monoclonal antibody with human IgG1 constant domain. The mouse monoclonal antibody was obtained from a mouse immunized with recombinant SARS-CoV-2 Nucleocapsid Protein. This chimeric antibody is purified by Protein A affinity chromatography.

• Host:

  HEK293

• Origin Species:

  Mouse

• Target:

  Nucleocapsid protein

• Conjugation:

  Biotin-labeled

• Tag:

  Human IgG1 | Human Kappa

• Stability:

  ● The product MUST be stored at -70°C or lower upon receipt; ● -70°C for 3 months under sterile conditions. Please avoid repeated freeze-thaw cycles.

• Purity:

  95%

• Bioactivity:

  Immobilized Biotinylated Anti-SARS-CoV-2 Nucleocapsid Antibody, Chimeric mAb, Human IgG1 (AM223) (Cat. No. NUN-BM272) at 1 μg/mL (100 μL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 μg/well) plate can bind SARS-CoV-2 Nucleocapsid protein, His Tag (Cat. No. NUN-C5227) with a linear range of 0.2-6 ng/mL (Routinely tested).

• Format:

  Liquid

• Buffer:

  PBS, pH7.4

• Shipping Conditions:

  Dry ice

• Storage Conditions:

  -70°C

• Package Size:

  1mg*1

• Species:

  Mouse

• CAS Number:

  9007-83-4