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TCF199

CAT: 0804-HY-162838Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-162838Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TCF199 is an allosteric stabilizer that stabilizes the 14-3-3/TAZ peptide interaction, binding to the 14-3-3ζ/E R α peptide and 14-3-3ζ/Chibby peptide. TCF199 has a Kd value of 122 μM for its interaction with 14-3-3/TAZ[1].
UNSPSC
12352211
Target
Estrogen Receptor/ERR
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/tcf199.html
Smiles
[H][C@@]12CCCC[C@@]1(COC(NC3=CC=CC=C3)=O)CCCN2
Molecular Formula
C17H24N2O2
Molecular Weight
288.38
References & Citations
[1]Blaž Andlovic, et al. Fragment-Based Interrogation of the 14-3-3/TAZ Protein-Protein Interaction. Biochemistry. 2024 Sep 3;63 (17) :2196-2206.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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