(-) -Vesamicol

• Description :

  (-) -Vesamicol (AH5183) is an inhibitor of acetylcholine transport into synaptic vesicles, with the IC50 of 75 nM[1]. (-) -Vesamicol can be used for release and recycling of synaptic vesicles study[1].

• Product Name Alternative :

  AH5183

• UNSPSC :

  12352005

• Target :

  MAChR

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/minus-vesamicol.html

• Purity :

  99.35

• Solubility :

  DMSO : 12.5 mg/mL (ultrasonic)

• Smiles :

  O[C@H]1[C@H](N2CCC(C3=CC=CC=C3)CC2)CCCC1

• Molecular Formula :

  C17H25NO

• Molecular Weight :

  259.39

• References & Citations :

  [1]Searl T, et al. Acetylcholine recycling and release at rat motor nerve terminals studied using (-) -vesamicol and troxpyrrolium. J Physiol. 1991;444:99-116.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [112709-59-8]