AZD-4205

CAT: 0026-B3124-1Size: 1 mgDry Ice: NoHazardous: No
CAT#:0026-B3124-1Size:1 mg
Selected
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
AZD-4205 is a highly selective Janus Kinase 1 (JAK1) inhibitor with an IC₅₀ of 0.07 μM. It shows antitumor activity in combination with the EGFR inhibitor, osimertinib, in a preclinical non-small-cell lung cancer xenograft NCI-H1975 model. It targets cancer stem cell associated signalling pathway and microenvironment and is being evaluated in phase II clinical trials to treat advanced non-small-cell lung cancer.
Shipping Conditions
Gel Pack
Storage Conditions
-20ºC
Shelf Life
36 months