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Anti-TrpC4 Antibody

CAT: 1303-75-119Size: 100 µLDry Ice: NoHazardous: No
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CAT#:1303-75-119Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Short transient receptor potential channel 4 or TrpC4 is encoded by the gene TrpC4. TrpC4 belongs to the transient receptor family, a group of membrane bound ion channels that have a relatively non-selective permeability to cations, including sodium, calcium and magnesium. This protein is thought to have a role as a cell-cell contact-dependent endothelial calcium entry channel. Trpc4 is found in many tissues including CNS, placenta, heart, smooth muscle, testis, kidney and brain. Mutations in this gene areassociated with generalized epilepsy with photosensitivity.
Description
Our Anti-TrpC4 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N77/15. It detects human, mouse, and rat TrpC4, and is purified by Protein A chromatography. It is great for use in IHC, ICC, IP, WB.
Short Description
Our Anti-TrpC4 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N77/15. It detects human, mouse, and rat TrpC4, and is purified by protein a chromatography. It is great for use in WB, IHC, ICC, IP, ELISA.
Synonyms
Short transient receptor potential channel 4 (Trp4) (TrpC4) (Capacitative calcium entry channel 1) (CCE1)
Gene Name
Trpc4
UniProt
O35119
Host
Mouse
Reactivity
Human, Mouse, and Rat
Immunogen
Synthetic peptide amino acids 930-947 (FKSEKVVVEDTVPIIPKE) of rat TrpC4 (accession number O35119)
Target
TrpC4
Clonality
Monoclonal
Isotype
IgG2b
Clone
N77/15
Type
Primary Antibody
Applications
WB, IHC, ICC, IP, ELISA
Field of Research
Ion Channels and Modulators/Trp Channels
Concentration
1 mg/mL
Format
Purified by Protein A chromatography
Buffer
10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.46
Molecular Weight
110 kDa
Shipping Conditions
Shipped on ice packs
Storage Conditions
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Notes
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
Specificity
No cross-reactivity reported
Quality Control
Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.
Recommended Usage
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
Physical Properties
Liquid
Immunogen Species
Rat
ICC Quality Control
1
Conjugate
Unconjugated
RRID
AB_2256454

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