Nesvacumab

• UNSPSC Description:

  Nesvacumab is a fully human immunoglobulin G1 (IgG1) monoclonal antibody that specifically binds and inactivates the Tie2 receptor ligand Angiopoietin-2 (Ang2) with high affinity, but shows no binding to Ang1[1].

• Target Antigen:

  Others

• Type:

  Inhibitory Antibodies

• Related Pathways:

  Others

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology; Cardiovascular Disease; Cancer

• Assay Protocol:

  https://www.medchemexpress.com/nesvacumab.html

• Purity:

  99.11

• Solubility:

  H2O

• Smiles:

  [Nesvacumab]

• References & Citations:

  [1]Kyriakos P Papadopoulos, et al. A Phase I First-in-Human Study of Nesvacumab (REGN910), a Fully Human Anti-Angiopoietin-2 (Ang2) Monoclonal Antibody, in Patients with Advanced Solid Tumors. Clin Cancer Res. 2016 Mar 15;22(6):1348-55.

• Shipping Conditions:

  Dry Ice

• Storage Conditions:

  Store at -80°C for 2 years

• Clinical Information:

  Phase 1

• CAS Number:

  1296818-77-3