NH2-PEG8-acid

• UNSPSC Description:

  NH2-PEG8-acid is a non-cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. NH2-PEG8-acid also is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2].

• Target Antigen:

  ADC Linker; PROTAC Linkers

• Type:

  ADC Related

• Related Pathways:

  Antibody-drug Conjugate/ADC Related;PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/nh2-peg8-acid.html

• Purity:

  98.0

• Solubility:

  DMSO : 50 mg/mL (ultrasonic)

• Smiles:

  O=C(O)CCOCCOCCOCCOCCOCCOCCOCCOCCN

• Molecular Weight:

  441.51

• References & Citations:

  [1]Michael Nathaniel ALONSO, et al. Antibody adjuvant conjugates. WO2018009916A1.|[2]"An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. "

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Clinical Information:

  No Development Reported

• CAS Number:

  756526-04-2